Sodium Citrate (Trisodium Citrate) Chemical Formula
Specifications
| Tests | Specifications |
|---|---|
| Description | Colorless crystals or white, crystalline powder. |
| Solubility | Freely soluble in water and very soluble in boiling water. Insoluble in alcohol. |
| Identification | A) solution (1 in 20) responds to the test for Sodium and for citrate. Sodium: A dense precipitate is formed. Citrate: A light red colour is produced. |
| Alkalinity | No pink colour is produced by 1 drop of phenolphthalein TS. |
| Water | Between 10.0% and 13.0%. Dry it at 180°C for 18 hours. |
| Alkalinity | Not more than 0.2 ml of 0.1M hydrochloric acid or 0.1M sodium Hydroxide is required to change the colour of the indicator. |
| Tartrate | No crystalline precipitate is formed. |
| Heavy Metals | Not more than 0.001%. |
| Assay | 99.0 % to 100.5 % (On Anhydrous Basis) |
FAQs (Frequently Asked Questions)
Sodium citrate acts as an anticoagulant by chelating, or binding, free calcium ions in the blood. Sodium citrate prevents blood from clotting by locking onto calcium. Since blood needs calcium to clot, removing it keeps blood fluid and safe during medical procedures like transfusions and dialysis.
Sodium citrate is the sodium salt of citric acid. It is alkaline, mildly salty in taste, and functions as a buffer and emulsifier. Citric acid is the parent organic acid. It is sour, acidic, and primarily used as a flavoring and preservative. Despite sharing the citrate backbone, they serve distinct roles across food, pharma, and industrial applications.
Yes. Sodium citrate is recognized as Generally Recognized As Safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is approved as a food additive in the European Union under the code E331. It is also permitted under Codex Alimentarius standards globally, making it one of the most universally approved food and pharmaceutical ingredients in the world.
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